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metformin is associated with weight loss when used to treat diabetes and thus differs from a number of other antidiabetic medications that are associated with weight stability or gain 2,3 .
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you should not use glipizide and metformin if you have severe kidney disease, or if you are in a state of diabetic ketoacidosis call your doctor for treatment with insulin .
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those who do experience lactic acidosis during metformin treatment, seem to have other complications that cause it, suggesting that metformin is not to be blamed.
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