Patients were randomized to receive either placebo or trileptal given as 1500 mg day on day 1 and 2400 mg day thereafter for an additional nine days, or until one of the following three exit criteria occurred 1 the occurrence of a fourth partial seizure, excluding day 1, 2 two new-onset secondarily generalized seizures, where such seizures were not seen in the one-year period prior to randomization, or 3 occurrence of serial seizures or status epilepticus.
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if you have a history of seizures, you may suddenly lose consciousness while you are taking trileptal.
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as with most antiepileptic drugs, trileptal should generally be withdrawn gradually because of the risk of increased seizure frequency and status epilepticus see dosage and administration and clinical studies .
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although some psychiatrists prescribe trileptal to treat bipolar disorder, research hasn t shown definitively that it s effective.
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table 5 lists adverse reactions in a controlled clinical study of monotherapy in adults not previously treated with other aeds that occurred in at least 2 of adult patients with epilepsy treated with trileptal or placebo and were numerically more common in the patients treated with trileptal.
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